3-cycloalkyl-propanamides.

ABSTRACT

A compound selected from the group consisting of all tautomeric forms of a cycloalkyl-propanamide of the formula    &lt;IMAGE&gt;  I  wherein R1 is cycloalkyl of 3 to 6 carbon atoms, R2 is hydrogen or alkyl of 1 to 3 carbon atoms, R3, R4, R5, R6 and R7 are individually selected from the group consisting of hydrogen, halogen, -NO2, azido, -CN, alkyl, alkoxy and alkylthio of 1 to 6 carbon atoms, -(CH2)m-CF3, -O-(CH2)m-CF3, -S-(CH2)m-CF3, m is an integer from 0 to 3, -CF2-Hal, -OCF2-Hal,   &lt;IMAGE&gt;    &lt;IMAGE&gt;   n is an integer from 1 to 3, Hal, Hal1, and Hal2 and Hal3 are individually halogen, and -COR&#39;, R&#39; is -OH or alkyl or alkoxy of 1 to 3 carbon atoms or R4 and R5 together are -O-CH2-O- and their non-toxic, pharmaceutically acceptable basic salts having anti-inflammatory activity.



